Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lncRNA-HEIH
   Synonyms HEIH, HCCAT2, LINC-HEIH, LINC00848, lncRNA-HEIH
   Region GRCh38_5:180829954-180831605    Sequence
   Ensembl ENSG00000278970
   RefSeq NR_045680
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods microarray, qPCR, RIP, RNA pull-down assay etc.
   Sample HCC tissues, cell lines (Huh7, HepG2)
   Expression Pattern up-regulated
   Function Description

The transcript levels of lncRNA-HEIH were higher in HCC tissues when compared with the corresponding non-tumor liver tissues from the same donor. And we found that patients with high lncRNA-HEIH expression in HCC had significantly worse prognosis than those with low lncRNA-HEIH expression.

   Pubmed ID 21769904
   Year 2011
   Title Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans.
   External Links
   Links for  lncRNA-HEIH GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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