Detail
| LncRNA Name | lncRNA-HIT |
| Synonyms | NA |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Luciferase reporter assay etc. |
| Sample | breast cancer tissues, cell lines (NMuMG, 4T1) |
| Expression Pattern | up-regulated |
| Function Description | The level of expression of lncRNA-HIT in normal breast tissue was low and gradually increased to invasive carcinoma suggesting lncRNA-HIT may play a role in tumor progression in humans. These data further support the findings demonstrating the involvement of lncRNA-HIT in EMT and invasion as observed in NMuMG and 4T1 cells, and suggest that conserved human lncRNA-HIT could play a pivotal role in breast cancer metastasis. |
| Pubmed ID | 25605728 |
| Year | 2015 |
| Title | Long non-coding RNAs regulated by TGFB1 lncRNA-HIT mediated TGFB1-induced epithelial to mesenchymal transition in mammary epithelia. |
| External Links |
| Links for lncRNA-HIT | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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