Detail
LncRNA Name | lncRNA-JADE |
Synonyms | JADRR, LINC00915, lncRNA-JADE |
Region | GRCh38_4:128768228-128769948 Sequence |
Ensembl | ENSG00000280711 |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | microarray, qPCR, RNAi, Western blot, RIP, in vitro knockdown etc. |
Sample | breast cancer tissues, cell lines (293T, NIH3T3, MCF7, 4T1-luciferase etc.) |
Expression Pattern | up-regulated |
Function Description | Markedly higher levels of lncRNA-JADE were observed in human breast tumours in comparison with normal breast tissues. Knockdown of lncRNA-JADE significantly inhibited breast tumour growth in vivo. |
Pubmed ID | 24097061 |
Year | 2013 |
Title | A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation. |
External Links |
Links for lncRNA-JADE | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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