Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lncRNA-LET
   Synonyms NPTN-IT1, lncRNA-LET
   Region GRCh38_15:73567012-73569294    Sequence
   Ensembl ENSG00000281183
   RefSeq NR_103844
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name cervical cancer
   ICD-0-3 C53  
   Methods qPCR etc.
   Sample cervical cancer tissues
   Expression Pattern down-regulated
   Function Description

The results showed that lncRNA LET expression in cervical cancer tissues was significantly down-regulated compared with the adjacent non-tumor tissues. Decreased lncRNA LET expression was significantly correlated with FIGO stage, lymph node metastasis, and depth of cervical invasion, but not other clinical characteristics.

   Pubmed ID 25755778
   Year 2015
   Title Low expression of long non-coding RNA LET inhibits carcinogenesis of cervical cancer.
   External Links
   Links for  lncRNA-LET GenBank       HGNC       lncrnadb       Noncode
   Links for  cervical cancer Omim       Cosmic

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