Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lncRNA-LET
   Synonyms NPTN-IT1, lncRNA-LET
   Region GRCh38_15:73567012-73569294    Sequence
   Ensembl ENSG00000281183
   RefSeq NR_103844
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR etc.
   Sample gastric cancer tissues
   Expression Pattern down-regulated
   Function Description

We found that lncRNA LET expression was markedly down-regulated in tumor tissues compared with adjacent non-tumor tissues, and associated with depth of invasion, lymph node metastasis, distant metastasis, and TNM stage. Univariate and multivariate analyses showed that low lncRNA LET expression was an independent poor prognostic factor for gastric cancer patients.

   Pubmed ID 25674261
   Year 2015
   Title Down-regulation of long non-coding RNA LET is associated with poor prognosis in gastric cancer.
   External Links
   Links for  lncRNA-LET GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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