Detail
LncRNA Name | lncRNA-URHC |
Synonyms | NA |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR, Western blot etc. |
Sample | cell line |
Expression Pattern | up-regulated |
Function Description | LncRNA-URHC expression was significantly increased in colorectal cancer cells compared with normal cells, and the expression of lncRNA-URHC in colorectal cancer cells was higher than that in the normal cell. After down-regulated the expression of lncRNA-URHC, the proliferation and invasion of colorectal cancer cells were decreased, while cells apoptosis was promoted. Down-regulation of lncRNA-URHC could enhance the expression of E-cadherin and reduce the expression of N-cadherin, vimentin and snail. |
Pubmed ID | 29630109 |
Year | 2018 |
Title | Effects of long non-coding RNA URHC on proliferation, apoptosis and invasion of colorectal cancer cells. |
External Links |
Links for lncRNA-URHC | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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