Detail
| LncRNA Name | LncSOX4 |
| Synonyms | NA |
| Region | GRCh38_6:21592768-21598619 Sequence |
| Ensembl | ENSG00000124766 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, Northern blot |
| Sample | osteosarcoma tissue, cell lines (293T, Mg63, U-20S) |
| Expression Pattern | up-regulated |
| Function Description | LncSox4 silencing attenuated but lncSox4 overexpression promoted cell viability (all P < 0.001) and migration (P < 0.01) in the Mg63 cells.we found lncSox4 regulation of osteosarcoma is involved in B-catenin, and overexpression of lncSox4 could stable B-catenin expression. |
| Pubmed ID | 29441981 |
| Year | 2017 |
| Title | Long non-coding RNA Sox4 promotes proliferation and migration by activating Wnt/B-catenin signaling pathway in osteosarcoma. |
| External Links |
| Links for LncSOX4 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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