Detail
| LncRNA Name | LOC100130476 |
| Synonyms | RP11-356I2.4, LOC100130476 |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | esophageal squamous cell cancer |
| ICD-0-3 | |
| Methods | qPCR, Luciferase reporter assay, Cell proliferation assay etc. |
| Sample | primary ESCC tissues, cell lines (cell lines TE1, TE13, T.Tn, Eca109 etc.) |
| Expression Pattern | down-regulated |
| Function Description | Significant downregulation of LOC100130476 was detected in esophageal cancer cell lines and primary ESCC tumor tissues. Up-regulation of LOC100130476 led to the inhibition of proliferation and invasiveness of the cancer cells. |
| Pubmed ID | 27338851 |
| Year | 2016 |
| Title | Aberrant methylation-mediated downregulation of long noncoding RNA LOC100130476 correlates with malignant progression of esophageal squamous cell carcinoma. |
| External Links |
| Links for LOC100130476 | GenBank HGNC lncrnadb Noncode |
| Links for esophageal squamous cell cancer | Omim Cosmic |
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