Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name LOC285758
   Synonyms LINC01268
   Region GRCh38_6:113868013-113873351    Sequence
   Ensembl ENSG00000227502
   RefSeq NR_038863
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name acute myeloid leukemia
   ICD-0-3  M9861/3
   Methods Microarray, qPCR, Western blot
   Sample Bone marrow of acutemyeloid leukemia, cell lines (KG-1a, THP-1)
   Expression Pattern up-regulated
   Function Description

Our results showed that the proliferation of those two cell lines were inhibited after knock-down of LOC285758. enhancer lncRNA LOC285758 showed thesignificant association with the poor overall survival based on 197AML samples from TCGA.

   Pubmed ID 28203711
   Year 2017
   Title Genome-wide characterization of lncRNAs in acutemyeloid leukemia
   External Links
   Links for  LOC285758 GenBank       HGNC       lncrnadb       Noncode
   Links for  acute myeloid leukemia Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.