Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LSINCT5
   Synonyms NA
   Region GRCh38_5:2712591-2715237    Sequence
   Ensembl NA
   RefSeq NR_145480
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, Northern blot etc.
   Sample cell lines (HMEC, HCC1500, HCC1569 etc.)
   Expression Pattern up-regulated
   Function Description

Collectively, our results identified a new class of long stress responsive non-coding transcripts, LSINCTs, which have increased expression in response to DNA damage induced by NNK. LSINCTs interestingly also have increased expression in a number of cancer-derived cell lines, indicating that the expression is increased in both, correlating cellular stress and cancer.

   Pubmed ID 20214974
   Year 2010
   Title Identification of long stress-induced non-coding transcripts that have altered expression in cancer.
   External Links
   Links for  LSINCT5 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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