Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LUCAT1
   Synonyms LUCAT1, SCAL1
   Region GRCh38_5:91303029-91314402    Sequence
   Ensembl ENSG00000248323
   RefSeq NR_103548
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods RNA-seq, qPCR, Western blot etc.
   Sample cell lines (A2780, A2780-DR)
   Expression Pattern up-regulated
   Function Description

Here, we showed that expression of lin-RECK-3, H19, LUCAT1, LINC00961, and linc-CARS2-2 was enhanced in cisplatin-resistant A2780-DR cells, Lin-RECK-3, H19, LUCAT1, LINC00961, and linc-CARS2-2 showed significantly increased expression levels in A2780-DR cells.

   Pubmed ID 27193186
   Year 2016
   Title The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
   External Links
   Links for  LUCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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