Detail
LncRNA Name | LUNAR1 |
Synonyms | LUNAR1 |
Region | GRCh38_15:99014704-99031050 Sequence |
Ensembl | NA |
RefSeq | NR_126487 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | T cell acute lymphoblastic leukemia |
ICD-0-3 | M9835/3 |
Methods | RNA-seq, qPCR etc. |
Sample | blood |
Expression Pattern | up-regulated |
Function Description | We have shown that one specific Notch-regulated lncRNA, LUNAR1, is required for efficient T-ALL growth in vitro and in vivo due to its ability to enhance IGF1R mRNA expression and sustain IGF1 signaling. |
Pubmed ID | 25083870 |
Year | 2014 |
Title | Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia. |
External Links |
Links for LUNAR1 | GenBank HGNC lncrnadb Noncode |
Links for T cell acute lymphoblastic leukemia | Omim Cosmic |
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