Detail
| LncRNA Name | MACC1-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:20141916-20153531 Sequence |
| Ensembl | ENSG00000228598 |
| RefSeq | NR_046756 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RNA-seq,qPCR, Western blot, Luciferase reporter assay |
| Sample | cell lines (AGS, BGC803, BGC823, MKN45, SGC7901, GES-1), GC tissues |
| Expression Pattern | up-regulated |
| Function Description | Elevated expression of MACC1-AS1 in gastric cancer tissues is linked to poor prognosis and promotes malignant phenotype upon cancer cells. MACC1-AS1 is elevated under metabolic stress and facilitates metabolic plasticity by promoting MACC1 expression through mRNA stabilization |
| Pubmed ID | 29510730 |
| Year | 2018 |
| Title | The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1. |
| External Links |
| Links for MACC1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.