Detail
| LncRNA Name | MAGI2-AS3 |
| Synonyms | ENST00000414797 |
| Region | GRCh38_7:79452877-79471208 Sequence |
| Ensembl | ENSG00000234456 |
| RefSeq | NR_038343 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | qPCR, etc. |
| Sample | blood |
| Expression Pattern | down-regulated |
| Function Description | MAGI2-AS3 level significantly correlated with tumor-node-metastasis (TNM) stage (p=0.001 in TEPs, p=0.003 in plasma), lymph-node metastasis (p=0.016 in TEPs, p=0.023 in plasma), and distant metastasis (p=0.045 in TEPs, p=0.045 in plasma). Our data suggested that EGFRvIII can also be detected in blood platelets and there was no difference with detection in plasma. EGFRvIII RNA existed in both TEPs and plasma, but EGFR intracellular mutations cannot be detected in DNA of TEPs isolated from NSCLC. |
| Pubmed ID | 29922089 |
| Year | 2018 |
| Title | LncRNAs and EGFRvIII sequestered in TEPs enable blood-based NSCLC diagnosis. |
| External Links |
| Links for MAGI2-AS3 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.