Detail
| LncRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
| Region | GRCh38_11:65497688-65506516 Sequence |
| Ensembl | ENSG00000251562 |
| RefSeq | NR_002819 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | retinoblastoma |
| ICD-0-3 | C69.2 M9510/3 |
| Methods | qPCR, Western blot, Luciferase Reporter Assays |
| Sample | cell line (Y79) |
| Expression Pattern | up-regulated |
| Function Description | Results showed that the expression of - MALAT1 was significantly higher in Y79 cell line than ARPE-19 cell line (P<0.01). MiR-124 was up-regulated by MALAT1 silence and hence was identified as a target of MALAT1 (P<0.05 or P<0.001). |
| Pubmed ID | 28550678 |
| Year | 2017 |
| Title | Knockdown of Long Noncoding RNA (lncRNA) Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Inhibits Proliferation, Migration, and Invasion and Promoted Apoptosis By Targeting miR-124 in Retinoblastoma |
| External Links |
| Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
| Links for retinoblastoma | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.