Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AP000459
   Synonyms AP000459.7
   Region GRCh38_21:23477641-23490724    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods microarray, qPCR etc.
   Sample gastric cancer tissues
   Expression Pattern down-regulated
   Function Description

To confirm the reliability and validity of the microarray data, we selected 14 differentially expressed key lncRNAs and analyzed their actual expression levels in 30 advanced GC samples and paired adjacent non-tumor tissue samples with qRT-PCR. Results showed that, RP5-919F19, CTD-2541M15 and UCA1 expression was significantly higher in carcinoma than in adjacent non-tumor tissues. AP000459, LOC101928316, RP11-167N4 and LINC01071 expression was significantly lower in carcinoma than in adjacent non-tumor tissues.

   Pubmed ID 26718650
   Year 2016
   Title Differential expression profiles of long non-coding RNAs reveal potential biomarkers for identification of human gastric cancer.
   External Links
   Links for  AP000459 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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