Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MALAT1
   Synonyms MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA
   Region GRCh38_11:65497688-65506516    Sequence
   Ensembl ENSG00000251562
   RefSeq NR_002819
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR etc.
   Sample glioma tissues
   Expression Pattern up-regulated
   Function Description

LncRNA MALAT1 expression was increased in glioma tissues compared with paired adjacent brain normal tissues. Furthermore, lncRNA MALAT1 was associated significantly with WHO grade and tumor size. Moreover, the level of lncRNA MALAT1 expression was markedly correlated with the glioma patients' overall survival. Multivariate analysis suggested that increased lncRNA MALAT1 expression was a poor independent prognostic predictor for glioma patients.

   Pubmed ID 25613066
   Year 2015
   Title Long noncoding RNA MALAT1 associates with the malignant status and poor prognosis in glioma.
   External Links
   Links for  MALAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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