Detail
| LncRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
| Region | GRCh38_11:65497688-65506516 Sequence |
| Ensembl | ENSG00000251562 |
| RefSeq | NR_002819 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✔ |
| Methylation | ✘ |
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | microarray, qPCR, in vitro knockdown etc. |
| Sample | cell lines (SKOV3, 293T) |
| Expression Pattern | up-regulated |
| Function Description | The results showed that MALAT1 inhibition significantly suppressed tumorigenity in vitro and in vivo. Compared with the control cells, 921 genes in the MALAT1-knockdown cells were deregulated by at least two-fold. |
| Pubmed ID | 27313681 |
| Year | 2016 |
| Title | Inhibition of the long non-coding RNA MALAT1 suppresses tumorigenicity and induces apoptosis in the human ovarian cancer SKOV3 cell line. |
| External Links |
| Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
| Links for ovarian cancer | Omim Cosmic |
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