Detail
| LncRNA Name | APTR |
| Synonyms | APTR, RSBN1L-AS1 |
| Region | GRCh38_7:77657660-77696265 Sequence |
| Ensembl | ENSG00000214293 |
| RefSeq | NR_038361 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | glioblastoma |
| ICD-0-3 | M9440/3 |
| Methods | qPCR, RNAi, Northern blot, Luciferase reporter assay etc. |
| Sample | primary glioblastoma tissues, cell lines (A172, HCT116) |
| Expression Pattern | up-regulated |
| Function Description | We identified a novel lncRNA, APTR, that acts in trans to repress the CDKN1A/p21 promoter independent of p53 to promote cell proliferation. |
| Pubmed ID | 24748121 |
| Year | 2014 |
| Title | A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. |
| External Links |
| Links for APTR | GenBank HGNC lncrnadb Noncode |
| Links for glioblastoma | Omim Cosmic |
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