Detail
LncRNA Name | MALAT1 |
Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
Region | GRCh38_11:65497688-65506516 Sequence |
Ensembl | ENSG00000251562 |
RefSeq | NR_002819 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 M8046/3 |
Methods | qPCR etc. |
Sample | NSCLC tissues |
Expression Pattern | up-regulated |
Function Description | The novel MALAT-1 transcript is a noncoding RNA of more than 8000 nt expressed from chromosome 11q13. It is highly expressed in lung, pancreas and other healthy organs as well as in NSCLC. MALAT 1 expressed sequences are conserved across several species indicating its potentially important function.The identification of MALAT-1 emphasizes the potential role of noncoding RNAs in human cancer. |
Pubmed ID | 12970751 |
Year | 2003 |
Title | MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. |
External Links |
Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
Links for non small cell lung cancer | Omim Cosmic |
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