Detail
| LncRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
| Region | GRCh38_11:65497688-65506516 Sequence |
| Ensembl | ENSG00000251562 |
| RefSeq | NR_002819 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, RNAi, Western blot, MTT assay etc. |
| Sample | cell line (HeLa) |
| Expression Pattern | up-regulated |
| Function Description | The levels of MALAT1 were also significantly higher in the MALAT1 transfection group compared to the control group. Low levels of miRNA-143 and high levels of MALAT1 could potentiate proliferation of the cervical cancer cell line HeLa, and accelerate its invasion and migration via enhancement of vimentin and reduction of E-cadherin levels, respectively. |
| Pubmed ID | 28252165 |
| Year | 2017 |
| Title | Effects of miRNA-143 and the non-coding RNA MALAT1 on the pathogenesis and metastasis of HeLa cells. |
| External Links |
| Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
| Links for cervical cancer | Omim Cosmic |
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