Detail
| LncRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
| Region | GRCh38_11:65497688-65506516 Sequence |
| Ensembl | ENSG00000251562 |
| RefSeq | NR_002819 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | microarray, qPCR etc. |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | The increased expression of MALAT1 in HCC tissue may represent a good prognostic biomarker for curatively resected HCC. Terefore, in combination with other tumor prognostic factors, the determination of the expression levels of these lncRNAs may lead to a more accurate prediction of HCC prognosis.The increase in the expression levels of MALAT1 in HCC tissues was signifcantly correlated with better overall survival. |
| Pubmed ID | 29170515 |
| Year | 2017 |
| Title | Prognostic Value of Long NonCoding RNA HULC and MALAT1 Following the Curative Resection of Hepatocellular Carcinoma. |
| External Links |
| Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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