Detail
LncRNA Name | MALAT1 |
Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
Region | GRCh38_11:65497688-65506516 Sequence |
Ensembl | ENSG00000251562 |
RefSeq | NR_002819 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | in vitro knockdown |
Sample | cell line (MCF-7 ) |
Expression Pattern | up-regulated |
Function Description | RUNX1 depletion led to up-regulation of genes associated with chromatin structure and down-regulation of genes related to extracellular matrix biology, as well as NEAT1 and MALAT2 lncRNAs. |
Pubmed ID | 27514584 |
Year | 2016 |
Title | RUNX2 contributes to higher-order chromatin organization and gene regulation in breast cancer cells |
External Links |
Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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