Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MALAT1
   Synonyms MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA
   Region GRCh38_11:65497688-65506516    Sequence
   Ensembl ENSG00000251562
   RefSeq NR_002819
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods in vitro knockdown
   Sample cell line (MCF-7 )
   Expression Pattern up-regulated
   Function Description

RUNX1 depletion led to up-regulation of genes associated with chromatin structure and down-regulation of genes related to extracellular matrix biology, as well as NEAT1 and MALAT2 lncRNAs.

   Pubmed ID 27514584
   Year 2016
   Title RUNX2 contributes to higher-order chromatin organization and gene regulation in breast cancer cells
   External Links
   Links for  MALAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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