Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MALAT1
   Synonyms MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA
   Region GRCh38_11:65497688-65506516    Sequence
   Ensembl ENSG00000251562
   RefSeq NR_002819
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample breast cancer tissues, cell lines (ZR751, ZR7530, MCF7, SKBR3, BT474 and T47D)
   Expression Pattern up-regulated
   Function Description

MALAT1 expression was significantly up-regulated compared with adjacent normal tissues. Furthermore, of 204 breast cancer patients, high MALAT1 expression was associated with positive ER and progesterone receptor (PR) status.

   Pubmed ID 27191888
   Year 2016
   Title Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) interacts with estrogen receptor and predicted poor survival in breast cancer.
   External Links
   Links for  MALAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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