Detail
LncRNA Name | MALAT1 |
Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, PRO1073, MALAT-1, mascRNA |
Region | GRCh38_11:65497688-65506516 Sequence |
Ensembl | ENSG00000251562 |
RefSeq | NR_002819 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR etc. |
Sample | breast cancer tissues, cell lines (ZR751, ZR7530, MCF7, SKBR3, BT474 and T47D) |
Expression Pattern | up-regulated |
Function Description | MALAT1 expression was significantly up-regulated compared with adjacent normal tissues. Furthermore, of 204 breast cancer patients, high MALAT1 expression was associated with positive ER and progesterone receptor (PR) status. |
Pubmed ID | 27191888 |
Year | 2016 |
Title | Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) interacts with estrogen receptor and predicted poor survival in breast cancer. |
External Links |
Links for MALAT1 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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