Detail
| LncRNA Name | MA-linc1 |
| Synonyms | LINC01024, MA-linc1, MALINC1 |
| Region | GRCh38_5:140072857-140108630 Sequence |
| Ensembl | ENSG00000245146 |
| RefSeq | NR_102739 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✔ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, RNAi, Western blot etc. |
| Sample | cell lines (U2OS, SAOS-2) |
| Expression Pattern | up-regulated |
| Function Description | We employed qPCR to analyze MA-linc1 levels in four cell lines: U2OS and H1299 cells, as well as the human embryonic lung fibroblasts, WI38, and another human osteosarcoma cell line, SAOS-2, each expressing the conditionally active E2F1. This analysis demonstrated that activation of the ectopic E2F1 resulted in a significant increase in MA-linc1 RNA levels in all four cell lines. |
| Pubmed ID | 26337085 |
| Year | 2015 |
| Title | A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel. |
| External Links |
| Links for MA-linc1 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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