Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name MDC1-AS
   Synonyms MDC1-AS1, MDC1-AS
   Region GRCh38_6:30703067-30713184    Sequence
   Ensembl ENSG00000224328
   RefSeq NR_133647
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods microarray, qPCR etc.
   Sample bladder cancer tissues
   Expression Pattern down-regulated
   Function Description

The expression levels of MDC1-AS and MDC1 was down-regulated in bladder cancer. After over-expression of MDC1-AS, increased levels of MDC1 were observed in bladder cancer cells. We also found a remarkably inhibitory role of antisense lncRNA MDC1-AS on malignant cell behaviors in bladder cancer cells EJ and T24.

   Pubmed ID 25514464
   Year 2014
   Title A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer.
   External Links
   Links for  MDC1-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.