Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MEG3
   Synonyms MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1
   Region GRCh38_14:100779410-100861031    Sequence
   Ensembl ENSG00000214548
   RefSeq NR_002766
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name multiple myeloma
   ICD-0-3 C42.1  M9732/3
   Methods MSP-PCR etc.
   Sample blood, bone marrow
   Expression Pattern differential expression
   Function Description

Promoter hypermethylation was observed in 12 (57.14%) bone marrow samples and in 9 of 14 (64.28%) available peripheral blood samples. A correlation with disease stage was also observed and also with the disease subtype (IgG, 64.7%; IgA, 0; IgM, 100%).

   Pubmed ID 18650181
   Year 2008
   Title Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma.
   External Links
   Links for  MEG3 GenBank       HGNC       lncrnadb       Noncode
   Links for  multiple myeloma Omim       Cosmic

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