Detail
| LncRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 Sequence |
| Ensembl | ENSG00000214548 |
| RefSeq | NR_002766 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | meningioma |
| ICD-0-3 | M9530/0 |
| Methods | qPCR, Luciferase reporter assay, ISH etc. |
| Sample | meningioma tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that MEG3 mRNA is highly expressed in normal arachnoidal cells. However, MEG3 is not expressed in the majority of human meningiomas or the human meningioma cell lines IOMM-Lee and CH157-MN. There is a strong association between loss of MEG3 expression and tumor grade. |
| Pubmed ID | 20179190 |
| Year | 2010 |
| Title | Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. |
| External Links |
| Links for MEG3 | GenBank HGNC lncrnadb Noncode |
| Links for meningioma | Omim Cosmic |
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