Detail
| LncRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 Sequence |
| Ensembl | ENSG00000214548 |
| RefSeq | NR_002766 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 M8070/3 |
| Methods | microarray, MSP-PCR, RNAi, Western blot etc. |
| Sample | TSCC tissues, cell lines (SCC-15, CAL27 etc.) |
| Expression Pattern | down-regulated |
| Function Description | We report here that miR-26a and lncRNA MEG3 gene expression were both strongly reduced in TSCC compared with levels in matched nonmalignant tissues, and combined low expression levels of both miR-26a and MEG3 emerged as an independent prognostic factor for poor clinical outcome in TSCC patients. |
| Pubmed ID | 24343426 |
| Year | 2014 |
| Title | Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma. |
| External Links |
| Links for MEG3 | GenBank HGNC lncrnadb Noncode |
| Links for tongue squamous cell carcinoma | Omim Cosmic |
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