Detail
LncRNA Name | MEG3 |
Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
Region | GRCh38_14:100779410-100861031 Sequence |
Ensembl | ENSG00000214548 |
RefSeq | NR_002766 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✔ |
Cancer Name | pituitary adenoma |
ICD-0-3 | C75.1 M8272/0 |
Methods | qPCR etc. |
Sample | pituitary tumor tissues |
Expression Pattern | down-regulated |
Function Description | In summary, MEG3 and GADD45γ expression was significantly lost in most clinically non-functioning adenomas (78 and 92%, respetcively). Other assessed pituitary tumor phenotypes expressed both genes at significantly different levels, and, in some cases, with overexpression. |
Pubmed ID | 21850407 |
Year | 2012 |
Title | Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas. |
External Links |
Links for MEG3 | GenBank HGNC lncrnadb Noncode |
Links for pituitary adenoma | Omim Cosmic |
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