Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MEG3
   Synonyms MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1
   Region GRCh38_14:100779410-100861031    Sequence
   Ensembl ENSG00000214548
   RefSeq NR_002766
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR etc.
   Sample CRC and liver tissues
   Expression Pattern down-regulated
   Function Description

The expression levels of four lncRNAs (GAS5, H19, MEG3 and Yiya) were significantly different between liver metastases and primary tumors of stage IV CRC patients. Furthermore, the high expression levels of GAS5 and Yiya were significantly associated with future occurrence of liver metastases in early stage CRC patients.

   Pubmed ID 27391432
   Year 2016
   Title Long non-coding RNAs: novel prognostic biomarkers for liver metastases in patients with early stage colorectal cancer
   External Links
   Links for  MEG3 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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