Detail
| LncRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 Sequence |
| Ensembl | ENSG00000214548 |
| RefSeq | NR_002766 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | non-functioning pituitary adenoma |
| ICD-0-3 | C75.1 M8272/0 |
| Methods | qPCR etc. |
| Sample | pituitary adenoma tissues |
| Expression Pattern | down-regulated |
| Function Description | Our data indicate that the DLK1-MEG3 locus is silenced in NFAs. The growth suppression by miRNAs in PDFS cells is consistent with the hypothesis that the DLK1-MEG3 locus plays a tumor suppressor role in human NFAs. |
| Pubmed ID | 21871428 |
| Year | 2011 |
| Title | Silencing of the imprinted DLK1-MEG3 locus in human clinically nonfunctioning pituitary adenomas. |
| External Links |
| Links for MEG3 | GenBank HGNC lncrnadb Noncode |
| Links for non-functioning pituitary adenoma | Omim Cosmic |
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