Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MEG3
   Synonyms MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1
   Region GRCh38_14:100779410-100861031    Sequence
   Ensembl ENSG00000214548
   RefSeq NR_002766
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non-functioning pituitary adenoma
   ICD-0-3 C75.1  M8272/0
   Methods qPCR etc.
   Sample pituitary adenoma tissues
   Expression Pattern down-regulated
   Function Description

For GADD45γ, significantly lower expression levels were found in nonfunctioning adenomas compared with normal pituitary and somatotroph adenomas. P8 and MEG3 mRNA levels were significantly lower in nonfunctioning and corticotroph adenomas compared with normal pituitary.

   Pubmed ID 25126861
   Year 2014
   Title Expression analysis of GADD45γ, MEG3, and p8 in pituitary adenomas.
   External Links
   Links for  MEG3 GenBank       HGNC       lncrnadb       Noncode
   Links for  non-functioning pituitary adenoma Omim       Cosmic

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