Detail
| LncRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 Sequence |
| Ensembl | ENSG00000214548 |
| RefSeq | NR_002766 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, MTT assay etc. |
| Sample | cell lines (HepG2 and HuH-7) |
| Expression Pattern | up-regulated |
| Function Description | In result we found that the DNC dependent overexpression of miR-29a and miR-185 can down-regulate the expression of DNMT1, 3A and 3B and subsequently overexpresses MEG3. |
| Pubmed ID | 26321746 |
| Year | 2015 |
| Title | Dendrosomal curcumin increases expression of the long non-coding RNA gene MEG3 via up-regulation of epi-miRs in hepatocellular cancer. |
| External Links |
| Links for MEG3 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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