Detail
| LncRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 Sequence |
| Ensembl | ENSG00000214548 |
| RefSeq | NR_002766 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | cell lines (MKN74, MKN45, SGC7901, AGS), GC tissues |
| Expression Pattern | down-regulated |
| Function Description | MEG3 suppressed proliferation and metastasis of GC cells through inhibiting miR-21 expression.MiR-21 was a target of MEG3. |
| Pubmed ID | 29710493 |
| Year | 2018 |
| Title | LncRNA-MEG3 inhibits proliferation and metastasis by regulating miRNA-21 in gastric cancer. |
| External Links |
| Links for MEG3 | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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