Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MHENCR
   Synonyms NA
   Region GRCh38_20:63627227-63628824    Sequence
   Ensembl ENSG00000232442
   RefSeq NR_132417
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name melanoma
   ICD-0-3  M8720/3
   Methods qPCR, Western blot, RIP
   Sample malignant melanoma tissues, cell lines (A375 and SK-MEL-2)
   Expression Pattern up-regulated
   Function Description

In this study, we identified a novel lncRNA MHENCR which was upregulated in melanoma tissues and further upregulated in metastatic melanoma. Increased expression of MHENCR indicted poor survival of melanoma patients.

   Pubmed ID 28123636
   Year 2017
   Title Long noncoding RNA MHENCR promotes melanoma progression via regulating miR-425/489-mediated PI3K-Akt pathway
   External Links
   Links for  MHENCR GenBank       HGNC       lncrnadb       Noncode
   Links for  melanoma Omim       Cosmic

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