Detail
| LncRNA Name | MIR100HG |
| Synonyms | MIR100HG, AGD1, linc-NeD125, lncRNA-N2 |
| Region | GRCh38_11:122028327-122556721 Sequence |
| Ensembl | ENSG00000255248 |
| RefSeq | NR_024430 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR etc. |
| Sample | hepatocellular carcinoma tissues, cell lines (MHCC97L, SMCC-7721, Huh-7, MHCC97H and LO2) |
| Expression Pattern | up-regulated |
| Function Description | We totally identified a set of four lncRNAs(MIR100HG, SERHL, CTD-2574D22.4 and SNHG20) that were significantly correlated with patient's survival. We then measured the expression levels of these four lncRNAs using TCGA data, and found that it was significantly up-regulated in HCC tumors compared with normal tissues. Further analysis indicated that three lncRNAs showed a positive coefficient in univariate analysis(SERHL, CTD-2574D22 and SNHG20), suggesting that a higher level of expression was associated with shorter survival. The negative coefficient for the remaining one lncRNAs(MIR100HG)suggested that their higher expression levels were associated with longer survival. |
| Pubmed ID | 29684484 |
| Year | 2018 |
| Title | Characterization of long non-coding RNAs to reveal potential prognostic biomarkers in hepatocellular carcinoma. |
| External Links |
| Links for MIR100HG | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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