Detail
| LncRNA Name | MIR155HG |
| Synonyms | MIR155HG, BIC, MIRHG2, NCRNA00172 |
| Region | GRCh38_21:25561909-25575168 Sequence |
| Ensembl | ENSG00000234883 |
| RefSeq | NR_001458 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | qPCR etc. |
| Sample | cell lines (U251, U87) |
| Expression Pattern | down-regulated |
| Function Description | MEG3 and ST7OT1 are up-regulated in both cell lines under apoptosis induced using both agents. The induction of GAS5 is only clearly detected during DOX-induced apoptosis, whereas the up-regulation of neat1 and MIR155HG is only found during RES-induced apoptosis in both cell lines. However, TUG1, BC200 and MIR155HG are down regulated when necrosis is induced using a high dose of DOX in both cell lines. MIR155HG encompasses the pre-miR155 sequence, and elevated levels of MIR155HG are associated with elevated levels of miR-155, which is considered to be an onco-miRNA |
| Pubmed ID | 25645334 |
| Year | 2015 |
| Title | Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells |
| External Links |
| Links for MIR155HG | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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