Detail
| LncRNA Name | MIR503HG |
| Synonyms | MIR503HG, H19X, MIR503HG2, MGC16121, H19X |
| Region | GRCh38_X:134543337-134546632 Sequence |
| Ensembl | ENSG00000223749 |
| RefSeq | NR_024607 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | choriocarcinoma |
| ICD-0-3 | M9220/3 |
| Methods | qPCR, Cell transfection, Cell cycle assay etc. |
| Sample | placenta tissues, cell line (JEG-3) |
| Expression Pattern | down-regulated |
| Function Description | MIR503HG and LINC00629 were lower expressed in JEG-3 cell line than in normal placenta tissues. We found that the overexpression of both lincRNAs could inhibit migration and invasion in JEG-3 choriocarcinoma cell line.Furthermore, using the normal tissue panel, we observed a significant positive correlation between MIR503HG and LINC00629 lincRNAs, and also between both lincRNAs and the neighboring miRNAs: miR-424, miR450a, miR-450b-5p, miR-542-3p and miR-503 |
| Pubmed ID | 27023770 |
| Year | 2016 |
| Title | Placenta-Enriched LincRNAs MIR503HG and LINC00629 Decrease Migration and Invasion Potential of JEG-3 Cell Line. |
| External Links |
| Links for MIR503HG | GenBank HGNC lncrnadb Noncode |
| Links for choriocarcinoma | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.