Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MIR503HG
   Synonyms MIR503HG, H19X, MIR503HG2, MGC16121, H19X
   Region GRCh38_X:134543337-134546632    Sequence
   Ensembl ENSG00000223749
   RefSeq NR_024607
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods microarray, RIP etc.
   Sample hepatocellular carcinoma tissues, celllines (SMMC-7721 and Huh7)
   Expression Pattern up-regulated
   Function Description

Expression level of miR503HG is significantly associated with the time to recurrence and overall survival and is an independent risk factor for recurrence and survival. Enhanced expression of miR503HG could noticeably inhibit HCC invasion and metastasis in vitro and in vivo.

   Pubmed ID 29774077
   Year 2018
   Title Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-kB pathway in hepatocellular carcinoma
   External Links
   Links for  MIR503HG GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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