Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name MUC19
   Synonyms MUC19, MUC-19
   Region GRCh38_12:40393395-40570832    Sequence
   Ensembl ENSG00000205592
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name head and neck squamous cell carcinoma
   ICD-0-3 C76.0  M8070/3
   Methods microarray, qPCR etc.
   Sample blood
   Expression Pattern differential expression
   Function Description

To investigate the role of lncRNAs in HPV16 promoting MDSCs aggregation in HNSCC, we examined 4 lncRNAs (HOTAIR, PROM1, CCAT1 and MUC19) expression in 47 HPV-positive blood samples using qRT-PCR. It turns out that the expression of HOTAIR, PROM1, CCAT1, and MUC19 was negatively associated with the number of MDSCs in HPV-positive HNSCC.

   Pubmed ID 28159935
   Year 2017
   Title LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma.
   External Links
   Links for  MUC19 GenBank       HGNC       lncrnadb       Noncode
   Links for  head and neck squamous cell carcinoma Omim       Cosmic

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