Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name n340790
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name thyroid cancer
   ICD-0-3 C73.9  
   Methods qPCR, Western blot etc.
   Sample thyroid cancer tissues, cell line (SW579)
   Expression Pattern up-regulated
   Function Description

Here, we found that the lncRNA n340790 was highly expressed in human thyroid cancer tissues and was strongly correlated with the clinical characteristics of patients. There was a good prognostic value of n340790 for thyroid cancer. Furthermore, we discovered that n340790 could act as an endogenous sponge by directly binding to miR-1254 and downregulating miR-1254 expression.

   Pubmed ID 28559970
   Year 2017
   Title The lncRNA n340790 accelerates carcinogenesis of thyroid cancer by regulating miR-1254
   External Links
   Links for  n340790 GenBank       HGNC       lncrnadb       Noncode
   Links for  thyroid cancer Omim       Cosmic

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