Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NBAT1
   Synonyms NBAT1, CASC14, NBAT-1
   Region GRCh38_6:22134957-22147193    Sequence
   Ensembl ENSG00000260455
   RefSeq NR_034143
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods qPCR, Western blot etc.
   Sample ovarian cancer tissues, cell lines (A2780, TOV112D, HO-8910, OVCAR-3, and SKOV3)
   Expression Pattern down-regulated
   Function Description

We found that lncRNA NBAT-1 was obviously downregulated in OC tissue compared to normal ovarian tissue (P<0.001) which was free of OC, and the detected levels of NBAT-1 were associated with the International Federation of Gynecology and Obstetrics stage and tumor size guidelines. Moreover, it has been shown that lower levels of NBAT-1 predict poor outcomes of OC.

   Pubmed ID 28435289
   Year 2017
   Title Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer
   External Links
   Links for  NBAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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