Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NBAT1
   Synonyms NBAT1, CASC14, NBAT-1
   Region GRCh38_6:22134957-22147193    Sequence
   Ensembl ENSG00000260455
   RefSeq NR_034143
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name clear cell renal cell carcinoma
   ICD-0-3 C64.9  M8005/0
   Methods qPCR, RNAi etc.
   Sample ccRCC tissues, cell lines (786-O, ACHN, Caki-1 etc.)
   Expression Pattern down-regulated
   Function Description

NBAT-1 expression is significantly decreased in ccRCC tissues and renal cancer cells compared with adjacent normal tissues and normal human proximal tubule epithelial cell line HK-2, and its low level is associated with advanced features and poor prognosis. NBAT-1 is a novel molecular correlated with ccRCC progression and it may represent a prognostic biomarker and therapeutic target in renal cancer diagnosis and treatment.

   Pubmed ID 26097558
   Year 2015
   Title Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma.
   External Links
   Links for  NBAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  clear cell renal cell carcinoma Omim       Cosmic

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