Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name nc886
   Synonyms VTRNA2-1, CBL-3, CBL3, MIR886, MIRN886, VTRNA2, hvg-5, nc886, svtRNA2-1a
   Region GRCh38_5:136080470-136080597    Sequence
   Ensembl ENSG00000270123
   RefSeq NR_030583
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung adenocarcinoma
   ICD-0-3 C34  M8140/3
   Methods microarray, qPCR etc.
   Sample cell lines (HCC827 and HCC827-8-1)
   Expression Pattern down-regulated
   Function Description

To validate the results of the microarray, we chose a total of 7 differentially expressed lncRNA transcripts for RT-qPCR. The RT-qPCR results were consistent with that of the microarray, in that all 7 lncRNA transcripts were differentially expressed with the same trend (upregulated or downregulated) and reached statistical significance.

   Pubmed ID 27108960
   Year 2016
   Title Genome-wide profiling of long non-coding RNA expression patterns in the EGFR-TKI resistance of lung adenocarcinoma by microarray.
   External Links
   Links for  nc886 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung adenocarcinoma Omim       Cosmic

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