Detail
| LncRNA Name | ncRuPAR |
| Synonyms | NCRUPAR, NCRNA00193, ncR-uPAR |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NR_028375 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Immunohistochemistry etc. |
| Sample | CRC tissues |
| Expression Pattern | down-regulated |
| Function Description | Our results indicated that the expression of ncRuPAR was significantly downregulated in CRC compared with paired adjacent nontumor tissues, but the level of PAR-1 mRNA in cancerous tissues was significantly higher than in adjacent normal areas. The expression of ncRuPAR was significantly correlated with lymph node metastasis, distant metastasis, Duck's stage, differentiation, and TNM stage and was potentially negatively associated with the mRNA levels and EI scores of PAR-1. |
| Pubmed ID | 25119598 |
| Year | 2014 |
| Title | Downregulation of a long noncoding RNA-ncRuPAR contributes to tumor inhibition in colorectal cancer. |
| External Links |
| Links for ncRuPAR | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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