Detail
| LncRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta |
| Region | GRCh38_11:65422798-65426526 Sequence |
| Ensembl | ENSG00000245532 |
| RefSeq | NR_028272 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | malignant pleural mesothelioma |
| ICD-0-3 | M9050/3 |
| Methods | microarray, qPCR etc. |
| Sample | MPM tissues, cell lines (H28, H226, H2052, H2452, MSTO etc.) |
| Expression Pattern | up-regulated |
| Function Description | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. |
| Pubmed ID | 23976967 |
| Year | 2013 |
| Title | Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM). |
| External Links |
| Links for NEAT1 | GenBank HGNC lncrnadb Noncode |
| Links for malignant pleural mesothelioma | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.