Detail
LncRNA Name | NEAT1 |
Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta |
Region | GRCh38_11:65422774-65445540 Sequence |
Ensembl | ENSG00000245532 |
RefSeq | NR_028272 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR |
Sample | colorectal cancer cell line (HCT116) |
Expression Pattern | differential expression |
Function Description | Collectively, these findings identify Neat1 as a p53-regulated large intergenic ncRNA (lincRNA) with a key role in suppressing transformation and cancer initiation, providing fundamental new insight into p53-mediated tumor suppression. |
Pubmed ID | 28698299 |
Year | 2017 |
Title | Neat1 is a p53-inducible lincRNA essential for transformation suppression |
External Links |
Links for NEAT1 | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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