Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NEAT1
   Synonyms NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta
   Region GRCh38_11:65422774-65445540    Sequence
   Ensembl ENSG00000245532
   RefSeq NR_028272
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR
   Sample colorectal cancer cell line (HCT116)
   Expression Pattern differential expression
   Function Description

Collectively, these findings identify Neat1 as a p53-regulated large intergenic ncRNA (lincRNA) with a key role in suppressing transformation and cancer initiation, providing fundamental new insight into p53-mediated tumor suppression.

   Pubmed ID 28698299
   Year 2017
   Title Neat1 is a p53-inducible lincRNA essential for transformation suppression
   External Links
   Links for  NEAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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