Detail
LncRNA Name | NEAT1 |
Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta |
Region | GRCh38_11:65422774-65445540 Sequence |
Ensembl | ENSG00000245532 |
RefSeq | NR_028272 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | Burkitts lymphoma |
ICD-0-3 | M9687/3 |
Methods | qPCR, RNAi, Western blot etc. |
Sample | blood |
Expression Pattern | up-regulated |
Function Description | NEAT1 expression levels were validated by qPCR, demonstrating high baseline expression (average Cp = 21.3), and confirming p53-dependent induction . lncRNAs NEAT1 and lincRNA-p21 as novel elements of the p53-dependent DNA damage response machinery in CLL and lymphoma. |
Pubmed ID | 25971364 |
Year | 2015 |
Title | p53-dependent non-coding RNA networks in Chronic Lymphocytic Leukemia. |
External Links |
Links for NEAT1 | GenBank HGNC lncrnadb Noncode |
Links for Burkitts lymphoma | Omim Cosmic |
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