Detail
| LncRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta |
| Region | GRCh38_11:65422774-65445540 Sequence |
| Ensembl | ENSG00000245532 |
| RefSeq | NR_028272 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | chronic lymphocytic leukemia |
| ICD-0-3 | M9823/3 |
| Methods | qPCR, RNAi, Western blot etc. |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 expression levels were validated by qPCR, demonstrating high baseline expression (average Cp = 21.3), and confirming p53-dependent induction .lncRNAs NEAT1 and lincRNA-p21 as novel elements of the p53-dependent DNA damage response machinery in CLL and lymphoma. |
| Pubmed ID | 25971364 |
| Year | 2015 |
| Title | p53-dependent non-coding RNA networks in Chronic Lymphocytic Leukemia. |
| External Links |
| Links for NEAT1 | GenBank HGNC lncrnadb Noncode |
| Links for chronic lymphocytic leukemia | Omim Cosmic |
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